About Matthys du Toit

Matthys du Toit

MSc candidate — applied AI research

Hello! :)

Final-year MSc student finishing a thesis on connectome-constrained world models — using the wiring diagrams of real nervous systems as priors for agents that learn to predict and act. I care about the places where neuroscience and machine learning genuinely inform each other. This site collects my projects, writing, and CV.

selected research all →
2026 Connectome-constrained world models Using a real nervous system's wiring diagram as a structural prior for an agent's predictive model. 2025 Notes on JAX for biologically structured networks Practical patterns for sparse, masked, and graph-structured layers.
recent essays all →
2026 Prediction as the cortex's first principle Why 'the brain is a prediction machine' is more than a slogan — and where the analogy to ML breaks.